PGD

PGD Specialist
Dr. Vicken Sepilian is a highly skilled Infertility Specialist and Reproductive Endocrinologist. The doctor serves the residents of Los Angeles at his offices in Glendale, CA and Santa Monica, CA. For many patients he performs Preimplantation Genetic Diagnosis, or PGD. This procedure helps to identify genetic abnormalities in embryos that are established outside of the womb.

PGD Q & A

by Vicken Sepilian, MD

What is PGD?

Preimplantation Genetic Diagnosis, or PGD, is a testing procedure that determines if embryos created outside of the womb have any genetic abnormalities that would prevent them from developing properly. This type of testing can uncover embryos with an excessive amount of chromosomes, much like in children with Downs' Syndrome. Women who are over the age of 35 can experience a wide variety of fertility issues that have to do with the number of chromosomes or their structural rearrangement. If a woman has miscarried several times, a PGD test may hold the answers to why. It can also offer clues as to what can be done to prevent miscarriages from occurring in the future.


How is PGD Used?

Preimplantation Genetic Diagnosis can be used in different ways. It can be used to test for additional chromosomes or missing chromosomes or to test for various other problems like chromosome rearrangement and single gene disorders like Cystic Fibrosis, Huntington Disease, and Marfan Syndrome. Diseases that are caused by recessive genes can also be uncovered with this type of test. Cystic fibrosis is a disease that is caused by the presence of a recessive gene carried by one or both of the parents.


Who Should Have PGD Testing?

Preimplantation Genetic Diagnosis should be performed on embryos from any couple who has a medical history of genetic disorders of any kind. Women who have had numerous miscarriages may benefit from PGD testing simply because it identifies embryos that may not be able to survive once implanted within the womb. The testing can also show what genetic abnormalities may be present at conception. Doctors may also recommend PGD testing to couples who have had fertility problems in the past. Performing these types of tests can tell doctors what is preventing a woman from carrying an embryo to full term and producing a live birth. The testing reduces the possibility of abnormal embryos.

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